AWAT2 Antibody - #DF9149
| Product: | AWAT2 Antibody |
| Catalog: | DF9149 |
| Description: | Rabbit polyclonal antibody to AWAT2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Rabbit, Dog |
| Mol.Wt.: | 38 kDa; 38kD(Calculated). |
| Uniprot: | Q6E213 |
| RRID: | AB_2842345 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9149, RRID:AB_2842345.
Fold/Unfold
Acyl CoA wax alcohol acyltransferase 2; Acyl-CoA retinol O-fatty-acyltransferase; Acyl-CoA wax alcohol acyltransferase 2; ARAT; Awat2; AWAT2_HUMAN; DC4; Diacylglycerol O acyltransferase 2 like 4; Diacylglycerol O acyltransferase candidate 4; Diacylglycerol O-acyltransferase 2-like protein 4; Diacylglycerol O-acyltransferase candidate 4; hDC4; hWS; Long chain alcohol O fatty acyltransferase 2; Long-chain-alcohol O-fatty-acyltransferase 2; MFAT; Multifunctional O acyltransferase; Multifunctional O-acyltransferase; Retinol O-fatty-acyltransferase; Wax synthase 2; Wax synthase; WS;
Immunogens
Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas.
- Q6E213 AWAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDWKTPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6E213 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T176 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot |
Research Backgrounds
Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters. Shows a preference for medium chain acyl-CoAs from C12 to C16 in length and fatty alcohols shorter than C20, as the acyl donors and acceptors, respectively. Also possesses acyl-CoA retinol acyltransferase (ARAT) activity that catalyzes 11-cis-specific retinyl ester synthesis. Shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13-cis-retinol, and all-trans-retinol substrates.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas.
Monomer.
Belongs to the diacylglycerol acyltransferase family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.
· Organismal Systems > Digestive system > Vitamin digestion and absorption.
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