Product: ABLIM1 Antibody
Catalog: DF9145
Description: Rabbit polyclonal antibody to ABLIM1
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 88 kDa; 88kD(Calculated).
Uniprot: O14639
RRID: AB_2842341

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ABLIM1 Antibody detects endogenous levels of total ABLIM1.
RRID:
AB_2842341
Cite Format: Affinity Biosciences Cat# DF9145, RRID:AB_2842341.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ABLIM 1; ABLIM; abLIM-1; ABLIM-L; ABLIM-M; ABLIM-S; ABLIM1; ABLM1_HUMAN; Actin binding double zinc finger protein; Actin binding LIM protein 1; Actin binding LIM protein family member 1; Actin-binding double zinc finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; DKFZp781D0148; FLJ14564; KIAA0059; LIM actin binding protein 1; LIMAB 1; LIMAB1; Limatin; MGC1224; MGC125264; OTTHUMP00000020530; OTTHUMP00000020531; OTTHUMP00000020532; OTTHUMP00000020533; OTTHUMP00000020534; OTTHUMP00000020535; OTTHUMP00000020536; OTTHUMP00000020537; RGD1565768; RP11-317F20.1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O14639 ABLM1_HUMAN:

Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.

Sequence:
MPAFLGLKCLGKLCSSEKSKVTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF

PTMs - O14639 As Substrate

Site PTM Type Enzyme
T22 Phosphorylation
S28 Phosphorylation
K121 Ubiquitination
S215 Phosphorylation
S216 Phosphorylation
K234 Ubiquitination
K275 Ubiquitination
K345 Ubiquitination
T349 Phosphorylation
T351 Phosphorylation
S352 Phosphorylation
S353 Phosphorylation
S355 Phosphorylation
Y357 Phosphorylation
S358 Phosphorylation
S362 Phosphorylation
S363 Phosphorylation
S367 Phosphorylation
T371 Phosphorylation
Y373 Phosphorylation
Y383 Phosphorylation
K384 Ubiquitination
K393 Ubiquitination
Y396 Phosphorylation
T405 Phosphorylation
Y406 Phosphorylation
Y410 Phosphorylation
T411 Phosphorylation
S412 Phosphorylation
Y414 Phosphorylation
K417 Ubiquitination
S422 Phosphorylation
S426 Phosphorylation
T429 Phosphorylation
S431 Phosphorylation
T433 Phosphorylation
S435 Phosphorylation
Y439 Phosphorylation
S450 Phosphorylation
T451 Phosphorylation
S452 O-Glycosylation
S452 Phosphorylation
S455 Phosphorylation
S458 Phosphorylation
Y461 Phosphorylation
S462 Phosphorylation
S465 Phosphorylation
Y466 Phosphorylation
T467 Phosphorylation
T469 Phosphorylation
T502 Phosphorylation
Y505 Phosphorylation
Y522 Phosphorylation
Y528 Phosphorylation
K529 Methylation
K529 Ubiquitination
S538 Phosphorylation
S540 Phosphorylation
S541 Phosphorylation
K546 Ubiquitination
K549 Ubiquitination
S586 Phosphorylation
S587 Phosphorylation
S631 Phosphorylation
S632 Phosphorylation
S636 Phosphorylation
Y638 Phosphorylation
S640 Phosphorylation
S644 Phosphorylation
S646 Phosphorylation
S651 Phosphorylation
K652 Ubiquitination
S655 Phosphorylation
Y659 Phosphorylation
S669 Phosphorylation
T670 Phosphorylation
Y675 Phosphorylation
S677 Phosphorylation
Y678 Phosphorylation
Y688 Phosphorylation
T690 Phosphorylation
S706 Phosphorylation
Y718 Phosphorylation
T724 Phosphorylation
R726 Methylation

Research Backgrounds

Function:

May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.

Subcellular Location:

Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Associated with the cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.

Subunit Structure:

Binds F-actin. Interacts with ABRA.

Research Fields

· Organismal Systems > Development > Axon guidance.   (View pathway)

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