ALKBH2 Antibody - #DF9073
| Product: | ALKBH2 Antibody |
| Catalog: | DF9073 |
| Description: | Rabbit polyclonal antibody to ALKBH2 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 29kDa; 29kD(Calculated). |
| Uniprot: | Q6NS38 |
| RRID: | AB_2842269 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9073, RRID:AB_2842269.
Fold/Unfold
2OG Fe(II) oxy DC1; 9530023G02; ABH 2; ABH2; alkB alkylation repair homolog 2; ALKB2_HUMAN; ALKBH2 alkB; ALKBH2; Alkylated DNA repair protein alkB homolog; Alkylated DNA repair protein alkB homolog 2; Alkylation repair homolog 2; Alpha ketoglutarate dependent dioxygenase alkB homolog 2; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; EC 1.14.11.; FLJ99103; hABH2; mABH2; MGC90512; Oxy DC1;
Immunogens
Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
- Q6NS38 ALKB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6NS38 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K7 | Acetylation | Uniprot | |
| K7 | Sumoylation | Uniprot | |
| K7 | Ubiquitination | Uniprot | |
| K16 | Sumoylation | Uniprot | |
| K16 | Ubiquitination | Uniprot | |
| K34 | Acetylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| Y91 | Phosphorylation | Uniprot | |
| T93 | Phosphorylation | Uniprot | |
| K104 | Acetylation | Uniprot | |
| K104 | Ubiquitination | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| T252 | Phosphorylation | Uniprot |
Research Backgrounds
Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Nucleus.
Note: Detected in replication foci during S-phase.
Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
Belongs to the alkB family.
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