Product: INSL5 Antibody
Catalog: DF8991
Description: Rabbit polyclonal antibody to INSL5
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Bovine, Sheep, Rabbit
Mol.Wt.: 15 kDa; 15kD(Calculated).
Uniprot: Q9Y5Q6
RRID: AB_2842187

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Bovine(100%), Sheep(86%), Rabbit(90%)
Clonality:
Polyclonal
Specificity:
INSL5 Antibody detects endogenous levels of total INSL5.
RRID:
AB_2842187
Cite Format: Affinity Biosciences Cat# DF8991, RRID:AB_2842187.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

INSL5; INSL5_HUMAN; Insulin like peptide INSL5; Insulin-like peptide 5; Insulin-like peptide INSL5 A chain; MGC126695; MGC126697; PRO182; RIF2; RP24-72J16.1; UNQ156; UNQ156/PRO182;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9Y5Q6 INSL5_HUMAN:

Highly expressed in rectum with lower levels in uterus and ascending and descending colon.

Sequence:
MKGSIFTLFLFSVLFAISEVRSKESVRLCGLEYIRTVIYICASSRWRRHQEGIPQAQQAETGNSFQLPHKREFSEENPAQNLPKVDASGEDRLWGGQMPTEELWKSKKHSVMSRQDLQTLCCTDGCSMTDLSALC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Rabbit
90
Sheep
86
Pig
0
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in rectum with lower levels in uterus and ascending and descending colon.

Subunit Structure:

Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Family&Domains:

Belongs to the insulin family.

Research Fields

· Organismal Systems > Endocrine system > Relaxin signaling pathway.

Restrictive clause

 

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For Research Use Only.
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