Phospho-Thymidine Kinase 1/TK1 (Ser13) Antibody - #AF3068
| Product: | Phospho-Thymidine Kinase 1/TK1 (Ser13) Antibody |
| Catalog: | AF3068 |
| Description: | Rabbit polyclonal antibody to Phospho-Thymidine Kinase 1/TK1 (Ser13) |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 25kDa; 25kD(Calculated). |
| Uniprot: | P04183 |
| RRID: | AB_2834493 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF3068, RRID:AB_2834493.
Fold/Unfold
cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymidine kinase cytosolic; TK 1; TK 2; TK1; Tk1a; Tk1b; TK2;
Immunogens
- P04183 KITH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P04183 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| T8 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | P06493 (CDK1) , P24941 (CDK2) | Uniprot |
| S15 | Phosphorylation | Uniprot | |
| K16 | Ubiquitination | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| K32 | Acetylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| R70 | Methylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K164 | Acetylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| K211 | Ubiquitination | Uniprot | |
| K220 | Acetylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| C230 | S-Nitrosylation | Uniprot | |
| S231 | Phosphorylation | Uniprot |
Research Backgrounds
Phosphorylated on Ser-13 in mitosis.
Cytoplasm.
Homotetramer.
Belongs to the thymidine kinase family.
Research Fields
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
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