CDK5RAP1 Antibody - #DF8915
| Product: | CDK5RAP1 Antibody |
| Catalog: | DF8915 |
| Description: | Rabbit polyclonal antibody to CDK5RAP1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 67 kDa; 68kD(Calculated). |
| Uniprot: | Q96SZ6 |
| RRID: | AB_2842111 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8915, RRID:AB_2842111.
Fold/Unfold
2310066P17Rik; C20orf34; C42; CDK5 activator binding protein C42; CDK5 activator binding protein C42 like; CDK5 regulatory subunit associated protein 1; CDK5RAP1.3; CDK5RAP1.4; CGI 05; HSPC167; OTTMUSP00000016976; RP23-154J12.6; RP5-1187J4.1;
Immunogens
Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
- Q96SZ6 CK5P1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLAAGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPPKVLGLQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96SZ6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S37 | Phosphorylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| R298 | Methylation | Uniprot | |
| K346 | Ubiquitination | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| K396 | Ubiquitination | Uniprot | |
| S406 | Phosphorylation | Uniprot | |
| Y422 | Phosphorylation | Uniprot | |
| Y483 | Phosphorylation | Uniprot | |
| K487 | Ubiquitination | Uniprot | |
| K495 | Ubiquitination | Uniprot | |
| K531 | Ubiquitination | Uniprot | |
| K546 | Acetylation | Uniprot | |
| K546 | Ubiquitination | Uniprot | |
| T583 | Phosphorylation | Uniprot |
Research Backgrounds
Specifically inhibits CDK5 activation by CDK5R1.
Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Interacts with CDK5R1 (p35 form). CDK5RAP1, CDK5RAP2 and CDK5RAP3 show competitive binding to CDK5R1. Forms a complex with CDK5R1 and CDK5.
Belongs to the methylthiotransferase family. MiaB subfamily.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.