TSH2 Antibody - #DF8874

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Product: TSH2 Antibody
Catalog: DF8874
Description: Rabbit polyclonal antibody to TSH2
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 115 kDa; 115kD(Calculated).
Uniprot: Q9NRE2
RRID: AB_2842070

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(92%)
Clonality:
Polyclonal
Specificity:
TSH2 Antibody detects endogenous levels of total TSH2.
RRID:
AB_2842070
Cite Format: Affinity Biosciences Cat# DF8874, RRID:AB_2842070.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C20orf17; Cell growth inhibiting protein 7; FLJ33887; Ovarian cancer related protein 10-2; Ovarian cancer-related protein 10-2; OVC10-2; Serologically defined colon cancer antigen 33 like; Teashirt family zinc finger 2; Teashirt homolog 2; Teashirt zinc finger homeobox 2; TSH2; TSH2_HUMAN; TSHZ2; ZABC2; Zinc finger protein 218; ZNF218;

Immunogens

Immunogen:
Uniprot:

Q9NRE2(TSH2_HUMAN) >>Visit HPA database.

Gene(ID):
TSHZ2(128553)
Expression:
Q9NRE2 TSH2_HUMAN:

Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.

Sequence:
MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAAEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDVDEE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Chicken
92
Horse
0
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NRE2 As Substrate

Site PTM Type Enzyme
K28 Sumoylation
Y66 Phosphorylation
S69 Phosphorylation
S72 Phosphorylation
K302 Ubiquitination
S332 Phosphorylation
S355 Phosphorylation
S440 Phosphorylation
K461 Sumoylation
K480 Sumoylation
K601 Sumoylation
T639 Phosphorylation
K644 Acetylation
K645 Acetylation
S743 Phosphorylation
S746 Phosphorylation
S770 Phosphorylation
S785 Phosphorylation
K800 Sumoylation
K820 Sumoylation
S897 Phosphorylation
S980 Phosphorylation
S1018 Phosphorylation
S1020 Phosphorylation
S1025 Phosphorylation

Research Backgrounds

Function:

Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).

PTMs:

Sumoylated.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.

Subunit Structure:

Interacts (via homeobox domain) with APBB1 (via PID domain 1).

Family&Domains:

Belongs to the teashirt C2H2-type zinc-finger protein family.

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