SMG9 Antibody - #DF8870
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8870, RRID:AB_2842066.
Fold/Unfold
Chromosome 19 open reading frame 61; DKFZp564H1322; F17127_1; FLJ12886; Protein smg 9 homolog; Protein smg-9 homolog; Protein SMG9; SMG 9; smg9; SMG9_HUMAN; Suppressor with morphogenetic effect on genitalia protein 9,;
Immunogens
- Q9H0W8 SMG9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSESGHSQPGLYGIERRRRWKEPGSGGPQNLSGPGGRERDYIAPWERERRDASEETSTSVMQKTPIILSKPPAERSKQPPPPTAPAAPPAPAPLEKPIVLMKPREEGKGPVAVTGASTPEGTAPPPPAAPAPPKGEKEGQRPTQPVYQIQNRGMGTAAPAAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVRKSSALAEYSRLLA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H0W8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| Y12 | Phosphorylation | Uniprot | |
| K21 | Methylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| Y41 | Phosphorylation | Uniprot | |
| S53 | Phosphorylation | Uniprot | |
| T64 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| T114 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| T118 | Phosphorylation | Uniprot | |
| T122 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| T143 | Phosphorylation | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| R248 | Methylation | Uniprot | |
| K373 | Ubiquitination | Uniprot | |
| S451 | Phosphorylation | Uniprot | |
| K472 | Ubiquitination | Uniprot | |
| K508 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8. Plays a role in brain, heart, and eye development (By similarity).
Phosphorylated by SMG1.
Component of the SMG1C complex composed of SMG1, SMG8 and SMG9. Self-associates to form homodimers and forms heterodimers with SMG8; these assembly forms may represent SMG1C intermediate forms.
Belongs to the SMG9 family.
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