FAKD5 Antibody - #DF8845

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Product: FAKD5 Antibody
Catalog: DF8845
Description: Rabbit polyclonal antibody to FAKD5
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Horse, Rabbit, Dog
Mol.Wt.: 87kDa; 87kD(Calculated).
Uniprot: Q7L8L6
RRID: AB_2842042

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Horse(90%), Rabbit(90%), Dog(82%)
Clonality:
Polyclonal
Specificity:
FAKD5 Antibody detects endogenous levels of total FAKD5.
RRID:
AB_2842042
Cite Format: Affinity Biosciences Cat# DF8845, RRID:AB_2842042.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

dJ1187M17.5; FAKD5_HUMAN; FAST kinase domain-containing protein 5; FAST kinase domains 5; FASTKD5; FLJ13149; FLJ58294;

Immunogens

Immunogen:
Uniprot:

Q7L8L6(FAKD5_HUMAN) >>Visit HPA database.

Gene(ID):
FASTKD5(60493)
Expression:
Q7L8L6 FAKD5_HUMAN:

Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.

Sequence:
MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
90
Horse
90
Dog
82
Pig
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q7L8L6 As Substrate

Site PTM Type Enzyme
S7 Phosphorylation
S73 Phosphorylation
S81 Phosphorylation
K82 Ubiquitination
T83 Phosphorylation
K87 Ubiquitination
S95 Phosphorylation
T99 Phosphorylation
Y166 Phosphorylation
S171 Phosphorylation
K361 Ubiquitination
Y451 Phosphorylation
K507 Acetylation
T608 Phosphorylation
K615 Ubiquitination
C670 S-Nitrosylation
S676 Phosphorylation
T692 Phosphorylation
R704 Methylation
Y730 Phosphorylation
T761 Phosphorylation
S762 Phosphorylation

Research Backgrounds

Function:

Plays an important role in the processing of non-canonical mitochondrial mRNA precursors.

Subcellular Location:

Mitochondrion matrix>Mitochondrion nucleoid.
Note: Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.

Subunit Structure:

Found in a complex with GRSF1, DDX28, DHX30 and FASTKD2. Associates with the 12S mitochondrial rRNA (12S mt-rRNA).

Family&Domains:

Belongs to the FAST kinase family.

Restrictive clause

 

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