Product: HNRNPA0 Antibody
Catalog: DF8823
Description: Rabbit polyclonal antibody to HNRNPA0
Application: WB
Reactivity: Human, Mouse
Prediction: Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 31 kDa; 31kD(Calculated).
Uniprot: Q13151
RRID: AB_2842020

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
HNRNPA0 Antibody detects endogenous levels of total HNRNPA0.
RRID:
AB_2842020
Cite Format: Affinity Biosciences Cat# DF8823, RRID:AB_2842020.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; HNRPA0; ROA0_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Pig
0
Horse
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q13151 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S4 Phosphorylation
K8 Ubiquitination
S19 Phosphorylation
S21 Phosphorylation
K45 Ubiquitination
S47 Phosphorylation
T54 Phosphorylation
Y55 Phosphorylation
S68 Phosphorylation
T76 Phosphorylation
K80 Ubiquitination
S84 Phosphorylation P49137 (MAPKAPK2)
S88 Phosphorylation
K96 Acetylation
K96 Sumoylation
K96 Ubiquitination
K99 Sumoylation
K99 Ubiquitination
K106 Sumoylation
K106 Ubiquitination
S119 Phosphorylation
K126 Sumoylation
K126 Ubiquitination
K133 Acetylation
K133 Sumoylation
K133 Ubiquitination
S135 Phosphorylation
K138 Sumoylation
R139 Methylation
Y145 Phosphorylation
K154 Sumoylation
K154 Ubiquitination
K159 Acetylation
K159 Sumoylation
K159 Ubiquitination
K171 Sumoylation
K172 Sumoylation
K172 Ubiquitination
K176 Sumoylation
K176 Ubiquitination
Y180 Phosphorylation
S181 Phosphorylation
S188 Phosphorylation
R189 Methylation
R192 Methylation
R195 Methylation
R198 Methylation
R200 Methylation
R204 Methylation
K211 Sumoylation
Y217 Phosphorylation
Y231 Phosphorylation
Y234 Phosphorylation
Y265 Phosphorylation
K269 Sumoylation
S270 Phosphorylation
S279 Phosphorylation
S280 Phosphorylation
R284 Methylation
R291 Methylation
S303 Phosphorylation

Research Backgrounds

Function:

mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs.

PTMs:

Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA.

Arg-291 is dimethylated, probably to asymmetric dimethylarginine.

Subcellular Location:

Nucleus.
Note: Component of ribonucleosomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.