Product: FSBP Antibody
Catalog: DF8766
Description: Rabbit polyclonal antibody to FSBP
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Bovine, Sheep, Rabbit
Mol.Wt.: 19 kDa; 35kD(Calculated).
Uniprot: O95073
RRID: AB_2841970

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Zebrafish(86%), Bovine(82%), Sheep(82%), Rabbit(82%)
Clonality:
Polyclonal
Specificity:
FSBP Antibody detects endogenous levels of total FSBP.
RRID:
AB_2841970
Cite Format: Affinity Biosciences Cat# DF8766, RRID:AB_2841970.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Fibrinogen silencer binding protein;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O95073 FSBP_HUMAN:

Expressed in multiple tissues including brain.

Sequence:
MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDHHPVAITVEVKQEEDIKPPPPLVLNSQQSDTLEQREEHELVHVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGEHFRSLLGYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Zebrafish
86
Bovine
82
Sheep
82
Rabbit
82
Horse
0
Dog
0
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95073 As Substrate

Site PTM Type Enzyme
K15 Ubiquitination
K73 Ubiquitination
K76 Ubiquitination
S193 Phosphorylation
S206 Phosphorylation
S298 Phosphorylation

Research Backgrounds

Function:

Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in multiple tissues including brain.

Subunit Structure:

Interacts with APBA1 (via PDZ 1 and 2 domains).

Research Fields

· Genetic Information Processing > Replication and repair > Homologous recombination.

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For Research Use Only.
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