Product: RHPN1 Antibody
Catalog: DF8714
Description: Rabbit polyclonal antibody to RHPN1
Application: WB IHC IF/ICC
Reactivity: Human
Mol.Wt.: 70,100kD; 74kD(Calculated).
Uniprot: Q8TCX5
RRID: AB_2841918

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
RHPN1 Antibody detects endogenous levels of total RHPN1.
RRID:
AB_2841918
Cite Format: Affinity Biosciences Cat# DF8714, RRID:AB_2841918.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

GTP Rho binding protein 1; GTP-Rho-binding protein 1; ODF5; Outer dense fiber of sperm tails 5; Rhophilin 1; Rhophilin-1; RHPN; Rhpn1; RHPN1_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP

PTMs - Q8TCX5 As Substrate

Site PTM Type Enzyme
S16 Phosphorylation
S24 Phosphorylation
T26 Phosphorylation
S92 Phosphorylation
K118 Ubiquitination
T157 Phosphorylation
S159 Phosphorylation
S163 Phosphorylation
S188 Phosphorylation
K411 Acetylation
K450 Ubiquitination
K505 Ubiquitination
R632 Methylation

Research Backgrounds

Function:

Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.

Subunit Structure:

Binds specifically to GTP-Rho. Interacts with ROPN1.

Family&Domains:

The PDZ domain mediates interaction with ROPN1.

Belongs to the RHPN family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.