POM121 Antibody - #DF8708

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Product: POM121 Antibody
Catalog: DF8708
Description: Rabbit polyclonal antibody to POM121
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Chicken
Mol.Wt.: 125 kDa; 128kD,83kD,125kD(Calculated).
Uniprot: Q96HA1 | A6NF01 | A8CG34
RRID: AB_2841912

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Chicken(100%)
Clonality:
Polyclonal
Specificity:
POM121 Antibody detects endogenous levels of total POM121.
RRID:
AB_2841912
Cite Format: Affinity Biosciences Cat# DF8708, RRID:AB_2841912.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DKFZp586G1822; DKFZp586P2220; FLJ41820; KIAA0618; MGC3792; Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; Nuclear pore membrane protein 121 kDa; Nucleoporin Nup121; NUP121; P121A_HUMAN; P145; Pom121; POM121 membrane glycoprotein; POM121A; Pore membrane protein of 121 kDa; POM121 transmembrane nucleoporin B (pseudogene); Putative nuclear envelope pore membrane protein POM 121B;

Immunogens

Immunogen:
Uniprot:

Q96HA1(P121A_HUMAN) >>Visit HPA database.

A6NF01(P121B_HUMAN) >>Visit HPA database.

A8CG34(P121C_HUMAN) >>Visit HPA database.

Gene(ID):
| POM121C(9883)
Sequence:
MSPAAAAAGAGERRRPIASVRDGRGRGCGGPARAVLLGLSLVGLLLYLVPAAAALAWLTVGATAAWWGLSREPRGSRPLSSFVRKARHRRPLSSFVRKARHRRTLFASPLAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAAAPEGQDLRDRPGRRPPARPAPRSPPPRSPPPRSPPPSPPTHRAHHVYPSLPTPLLRPSRRPSPRDCGTLPNRFVITPRRRYPIHQAQYSCLGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHTRKK

MSRRVRTSELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK

MSPAAAAAGAGERRRPIASVRDGRGRGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKARHRRTLFASPPAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPRSTPPSQPTHRVHHFYPSLPTPLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGLTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Chicken
100
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96HA1/A6NF01/A8CG34 As Substrate

Site PTM Type Enzyme
S2 Phosphorylation
S80 Phosphorylation
S81 Phosphorylation
S93 Phosphorylation
S94 Phosphorylation
S108 Phosphorylation
K112 Ubiquitination
S174 Phosphorylation
S179 Phosphorylation
R183 Methylation
S184 Phosphorylation
S188 Phosphorylation
R215 Methylation
R223 Methylation
R229 Methylation
Y253 Phosphorylation
S260 Phosphorylation
R265 Methylation
S269 Phosphorylation
T272 Phosphorylation
S283 Phosphorylation
S285 Phosphorylation
S298 Phosphorylation
K309 Ubiquitination
T311 Phosphorylation
S314 Phosphorylation
K317 Acetylation
K317 Ubiquitination
K319 Acetylation
K339 Ubiquitination
S345 Phosphorylation
S346 Phosphorylation
S348 Phosphorylation
S351 Phosphorylation
S371 Phosphorylation
S378 Phosphorylation
S380 Phosphorylation
S381 Phosphorylation
K387 Ubiquitination
S389 Phosphorylation
S391 Phosphorylation
S392 Phosphorylation
S393 Phosphorylation
S395 Phosphorylation
S396 Phosphorylation
T398 Phosphorylation
Y401 Phosphorylation
S409 Phosphorylation
S416 Phosphorylation
Y417 Phosphorylation
S424 Phosphorylation
K428 Methylation
K428 Ubiquitination
S434 Phosphorylation
S435 Phosphorylation
S438 Phosphorylation
S439 Phosphorylation
S442 Phosphorylation
S443 Phosphorylation
S445 Phosphorylation
T447 Phosphorylation
S464 Phosphorylation
S465 Phosphorylation
S476 Phosphorylation
T484 Phosphorylation
T485 Phosphorylation
S494 Phosphorylation
S496 Phosphorylation
T497 Phosphorylation
S500 Phosphorylation
S501 Phosphorylation
S513 Phosphorylation
K540 Ubiquitination
K541 Ubiquitination
S543 Phosphorylation
S626 Phosphorylation
K689 Ubiquitination
T693 O-Glycosylation
S694 O-Glycosylation
S697 Phosphorylation
T711 Phosphorylation
S712 Phosphorylation
S714 Phosphorylation
S715 Phosphorylation
K737 Acetylation
S738 O-Glycosylation
T945 Phosphorylation
S958 Phosphorylation
T1024 Phosphorylation
Site PTM Type Enzyme
S19 Phosphorylation
S22 Phosphorylation
S23 Phosphorylation
K124 Ubiquitination
K125 Ubiquitination
Site PTM Type Enzyme
S2 Phosphorylation
S80 Phosphorylation
S81 Phosphorylation
S95 Phosphorylation
K99 Ubiquitination
S161 Phosphorylation
T162 Phosphorylation
S165 Phosphorylation
T168 Phosphorylation
T180 Phosphorylation
T196 Phosphorylation
R200 Methylation
T204 Phosphorylation
R206 Methylation
S237 Phosphorylation
R242 Methylation
S246 Phosphorylation
S260 Phosphorylation
S262 Phosphorylation
S275 Phosphorylation
K286 Ubiquitination
T288 Phosphorylation
S291 Phosphorylation
K294 Ubiquitination
K316 Ubiquitination
S322 Phosphorylation
S323 Phosphorylation
S325 Phosphorylation
S328 Phosphorylation
S336 Phosphorylation
S341 Phosphorylation
S348 Phosphorylation
S355 Phosphorylation
S357 Phosphorylation
S358 Phosphorylation
K364 Ubiquitination
S366 Phosphorylation
S368 Phosphorylation
S369 Phosphorylation
S370 Phosphorylation
S372 Phosphorylation
S373 Phosphorylation
T375 Phosphorylation
Y378 Phosphorylation
T379 Phosphorylation
S380 Phosphorylation
S385 Phosphorylation
S392 Phosphorylation
S393 Phosphorylation
Y394 Phosphorylation
S401 Phosphorylation
K405 Methylation
K405 Ubiquitination
S411 Phosphorylation
S412 Phosphorylation
S415 Phosphorylation
S416 Phosphorylation
S419 Phosphorylation
S420 Phosphorylation
S422 Phosphorylation
T424 Phosphorylation
K431 Ubiquitination
S441 Phosphorylation
S442 Phosphorylation
S443 Phosphorylation
S444 Phosphorylation
T445 Phosphorylation
S453 Phosphorylation
T461 Phosphorylation
T462 Phosphorylation
S473 Phosphorylation
T474 Phosphorylation
S477 Phosphorylation
S478 Phosphorylation
S490 Phosphorylation
K517 Ubiquitination
K518 Ubiquitination
S520 Phosphorylation
S603 Phosphorylation
K666 Ubiquitination
T670 O-Glycosylation
S671 O-Glycosylation
S674 Phosphorylation
S692 Phosphorylation
S702 Phosphorylation
K714 Acetylation
S715 O-Glycosylation
T922 Phosphorylation
S935 Phosphorylation
T965 Phosphorylation
S967 Phosphorylation
T1003 Phosphorylation

Research Backgrounds

Function:

Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).

Subcellular Location:

Nucleus>Nuclear pore complex. Nucleus membrane>Single-pass membrane protein. Endoplasmic reticulum membrane>Single-pass membrane protein.
Note: Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Contains F-X-F-G repeats.

Belongs to the POM121 family.

Function:

Putative component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane (By similarity).

Subcellular Location:

Nucleus>Nuclear pore complex.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Contains F-X-F-G repeats.

Belongs to the POM121 family.

Function:

Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).

Subcellular Location:

Nucleus>Nuclear pore complex. Nucleus membrane>Single-pass membrane protein. Endoplasmic reticulum membrane>Single-pass membrane protein.
Note: Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Contains F-X-F-G repeats.

Belongs to the POM121 family.

Research Fields

· Genetic Information Processing > Translation > RNA transport.

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