STEAP1 Antibody - #DF8618
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8618, RRID:AB_2841822.
Fold/Unfold
2410007B19Rik; EC 1.16.1.-; Metalloreductase STEAP1; MGC19484; PRSS 24; PRSS24; Six transmembrane epithelial antigen of prostate; Six transmembrane epithelial antigen of the prostate 1; Six transmembrane epithelial antigen of the prostate; Six-transmembrane epithelial antigen of prostate 1; STEA1_HUMAN; STEAP 1; Steap; STEAP1;
Immunogens
- Q9UHE8 STEA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESRKDITNQEELWKMKPRRNLEEDDYLHKDTGETSMLKRPVLLHLHQTAHADEFDCPSELQHTQELFPQWHLPIKIAAIIASLTFLYTLLREVIHPLATSHQQYFYKIPILVINKVLPMVSITLLALVYLPGVIAAIVQLHNGTKYKKFPHWLDKWMLTRKQFGLLSFFFAVLHAIYSLSYPMRRSYRYKLLNWAYQQVQQNKEDAWIEHDVWRMEIYVSLGIVGLAILALLAVTSIPSVSDSLTWREFHYIQSKLGIVSLLLGTIHALIFAWNKWIDIKQFVWYTPPTFMIAVFLPIVVLIFKSILFLPCLRKKILKIRHGWEDVTKINKTEICSQL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UHE8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y27 | Phosphorylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| T160 | Phosphorylation | Uniprot | |
| Y178 | Phosphorylation | Uniprot | |
| Y188 | Phosphorylation | Uniprot | |
| Y219 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| K329 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| S337 | Phosphorylation | Uniprot |
Research Backgrounds
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
Endosome membrane>Multi-pass membrane protein.
Ubiquitously expressed. Highly expressed in prostate tumors.
Belongs to the STEAP family.
Research Fields
· Organismal Systems > Digestive system > Mineral absorption.
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