PANK2 Antibody | Affinity Biosciences

WB
IF/ICC

1/2

Western blot analysis of PANK2 using HT29 whole cell lysates.

Product:	PANK2 Antibody
Catalog:	DF8588
Description:	Rabbit polyclonal antibody to PANK2
Application:	WB IF/ICC
Reactivity:	Human
Mol.Wt.:	62 kDa; 63kD(Calculated).
Uniprot:	Q9BZ23
RRID:	AB_2841792

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Polyclonal

Specificity:

PANK2 Antibody detects endogenous levels of total PANK2.

RRID:

AB_2841792
Cite Format: Affinity Biosciences Cat# DF8588, RRID:AB_2841792.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

4933409I19Rik; AI642621; C20orf48; Hallervorden Spatz syndrome; HARP; hPANK2; HSS; MGC118448; MGC15053; mitochondrial; NBIA1; PANK2; PANK2_HUMAN; Pantothenate kinase 2 (Hallervorden Spatz syndrome); Pantothenate kinase 2; Pantothenate kinase 2 mitochondrial; Pantothenic acid kinase 2; PKAN; RP23 387C21.4;

Immunogens

Immunogen:

Uniprot:

Q9BZ23(PANK2_HUMAN) >>Visit HPA database.

Gene(ID):

PANK2(80025)

Expression:

Q9BZ23 PANK2_HUMAN:

Ubiquitous.

Sequence:

Q9BZ23 PANK2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MRRLGPFHPRVHWAAPPSLSSGLHRLLFLRGTRIPSSTTLSPPRHDSLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAAEEARRNPTLGGLLGRQRLLLRMGGGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQEPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLCGRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP

PTMs - Q9BZ23 As Substrate

Q9BZ23

Site	PTM Type	Source
S140	Phosphorylation	Uniprot
T142	Phosphorylation	Uniprot
S143	Phosphorylation	Uniprot
S168	Phosphorylation	Uniprot
S169	Phosphorylation	Uniprot
S171	Phosphorylation	Uniprot
S189	Phosphorylation	Uniprot
Y190	Phosphorylation	Uniprot
S191	Phosphorylation	Uniprot
T194	Phosphorylation	Uniprot
S195	Phosphorylation	Uniprot
S203	Phosphorylation	Uniprot
K231	Ubiquitination	Uniprot
K246	Ubiquitination	Uniprot
K250	Ubiquitination	Uniprot
K271	Ubiquitination	Uniprot
K279	Ubiquitination	Uniprot
K371	Ubiquitination	Uniprot
S395	Phosphorylation	Uniprot
Y400	Phosphorylation	Uniprot
Y405	Phosphorylation	Uniprot
S470	Phosphorylation	Uniprot
S471	Phosphorylation	Uniprot
S477	Phosphorylation	Uniprot
K486	Ubiquitination	Uniprot
K543	Ubiquitination	Uniprot

Research Backgrounds

Q9BZ23_PANK2_HUMAN

Function:

May be the master regulator of the CoA biosynthesis.

Subcellular Location:

Mitochondrion.

Cytoplasm.

Cytoplasm.

Cytoplasm.

Tissue Specificity:

Ubiquitous.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the type II pantothenate kinase family.

Research Fields

· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

PANK2 Antibody - #DF8588