REM1 Antibody - #DF8352
| Product: | REM1 Antibody |
| Catalog: | DF8352 |
| Description: | Rabbit polyclonal antibody to REM1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 33 kDa; 33kD(Calculated). |
| Uniprot: | O75628 |
| RRID: | AB_2841617 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8352, RRID:AB_2841617.
Fold/Unfold
E030011C07Rik; GD:REM; GES; GTP binding protein REM; GTP binding protein REM 1; GTP binding protein REM1; GTP-binding protein REM 1; GTPase GES; GTPase regulating endothelial cell sprouting; GTPase-regulating endothelial cell sprouting; MGC114556; MGC48669; OTTMUSP00000016855; Rad and Gem like GTP binding protein 1; Rad and Gem-like GTP-binding protein 1; RAS (RAD and GEM) like GTP binding; RAS like GTP binding; RAS like GTP binding protein REM; REM 1; Rem1; REM1_HUMAN; RP23-35I8.9;
Immunogens
Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate.
- O75628 REM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHNLAVL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75628 As Substrate
Research Backgrounds
Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate.
In vitro, interacts with calmodulin in a calcium-dependent manner.
Belongs to the small GTPase superfamily. RGK family.
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