Product: PCYOX1 Antibody
Catalog: DF8332
Description: Rabbit polyclonal antibody to PCYOX1
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 57 kDa; 57kD(Calculated).
Uniprot: Q9UHG3
RRID: AB_2841603

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
PCYOX1 Antibody detects endogenous levels of total PCYOX1.
RRID:
AB_2841603
Cite Format: Affinity Biosciences Cat# DF8332, RRID:AB_2841603.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EC 1.8.3.5; KIAA0908; PCL1; PCYOX_HUMAN; PCYOX1; Prenylcysteine lyase; Prenylcysteine oxidase 1; Prenylcysteine oxidase precursor;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UHG3 PCYOX_HUMAN:

Ubiquitous.

Sequence:
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL

PTMs - Q9UHG3 As Substrate

Site PTM Type Enzyme
T47 Phosphorylation
Y51 Phosphorylation
K62 Ubiquitination
K162 Ubiquitination
S171 Phosphorylation
Y174 Phosphorylation
S177 Phosphorylation
N196 N-Glycosylation
T202 Phosphorylation
K205 Ubiquitination
C258 S-Nitrosylation
Y308 Phosphorylation
N323 N-Glycosylation
Y339 Phosphorylation
N353 N-Glycosylation
K392 Ubiquitination
Y403 Phosphorylation
K415 Acetylation
K415 Ubiquitination
Y425 Phosphorylation
Y427 Phosphorylation
Y482 Phosphorylation
Y498 Phosphorylation

Research Backgrounds

Function:

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.

PTMs:

The protein is glycosylated at one or more potential N-glycosylation sites.

Subcellular Location:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Family&Domains:

Belongs to the prenylcysteine oxidase family.

Research Fields

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.