KRT12 Antibody - #DF8321
| Product: | KRT12 Antibody |
| Catalog: | DF8321 |
| Description: | Rabbit polyclonal antibody to KRT12 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 54 kDa; 54kD(Calculated). |
| Uniprot: | Q99456 |
| RRID: | AB_2841597 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8321, RRID:AB_2841597.
Fold/Unfold
CK-12; Cytokeratin-12; K12; K1C12_HUMAN; Keratin 12; Keratin; Keratin, type I cytoskeletal 12; Keratin-12; KRT12; type I cytoskeletal 12;
Immunogens
- Q99456 K1C12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEELM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q99456 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S22 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| Y139 | Phosphorylation | Uniprot | |
| K142 | Acetylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| Y161 | Phosphorylation | Uniprot | |
| T163 | Phosphorylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| Y262 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| Y429 | Phosphorylation | Uniprot |
Research Backgrounds
May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).
Cornea specific.
Heterotetramer of two type I and two type II keratins. Keratin-3 associates with keratin-12.
Belongs to the intermediate filament family.
Research Fields
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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