SSR1 Antibody | Affinity Biosciences

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Western blot analysis SSR1 using Jurkat whole cell lysates.

Product:	SSR1 Antibody
Catalog:	DF8244
Description:	Rabbit polyclonal antibody to SSR1
Application:	WB
Reactivity:	Human
Prediction:	Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.:	32 kDa; 32kD(Calculated).
Uniprot:	P43307
RRID:	AB_2841539

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Prediction:

Pig(100%), Zebrafish(80%), Bovine(100%), Horse(90%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(90%), Xenopus(90%)

Clonality:

Polyclonal

Specificity:

SSR1 Antibody detects endogenous levels of total SSR1.

RRID:

AB_2841539
Cite Format: Affinity Biosciences Cat# DF8244, RRID:AB_2841539.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

DKFZp781N23103; FLJ14232; FLJ22100; FLJ23034; FLJ78242; FLJ93042; PGP35; Signal sequence receptor alpha; Signal sequence receptor alpha subunit; Signal sequence receptor subunit alpha; SSR 1; SSR alpha; SSR-alpha; SSR1; SSRA_HUMAN; SSRalpha; Translocon associated protein alpha; Translocon associated protein alpha subunit; Translocon associated protein subunit alpha; Translocon-associated protein subunit alpha; TRAP a; TRAP-alpha; TRAPa; TRAPalpha;

Immunogens

Immunogen:

Uniprot:

P43307(SSRA_HUMAN) >>Visit HPA database.

Gene(ID):

SSR1(6745)

Sequence:

P43307 SSRA_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Pig

100

Bovine

100

Sheep

100

Dog

100

Rabbit

100

Horse

Xenopus

Chicken

Zebrafish

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P43307 As Substrate

P43307

Site	PTM Type	Enzyme	Source
S80	Phosphorylation		Uniprot
K91	Ubiquitination		Uniprot
K102	Ubiquitination		Uniprot
K110	Ubiquitination		Uniprot
N136	N-Glycosylation		Uniprot
Y156	Phosphorylation		Uniprot
N191	N-Glycosylation		Uniprot
T245	Phosphorylation		Uniprot
S246	Phosphorylation		Uniprot
S247	Phosphorylation		Uniprot
S254	Phosphorylation		Uniprot
T260	Phosphorylation		Uniprot
K266	Ubiquitination		Uniprot
S268	Phosphorylation	P06493 (CDK1)	Uniprot
S281	Phosphorylation		Uniprot
S284	Phosphorylation		Uniprot

Research Backgrounds

P43307_SSRA_HUMAN

Function:

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

Subcellular Location:

Endoplasmic reticulum membrane>Single-pass type I membrane protein.

Subunit Structure:

Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.

Family&Domains:

Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.

Belongs to the TRAP-alpha family.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)

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SSR1 Antibody - #DF8244