GFPT1 Antibody - #DF8232
| Product: | GFPT1 Antibody |
| Catalog: | DF8232 |
| Description: | Rabbit polyclonal antibody to GFPT1 |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
| Mol.Wt.: | 79 kDa; 79kD(Calculated). |
| Uniprot: | Q06210 |
| RRID: | AB_2841529 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8232, RRID:AB_2841529.
Fold/Unfold
CMS12; CMSTA1; D-fructose-6-phosphate amidotransferase 1; GFA; GFAT 1; GFAT; GFAT1; GFAT1m; GFPT; Gfpt1; GFPT1_HUMAN; GFPT1L; Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Glutamine--fructose-6-phosphate transaminase 1; Glutamine:fructose 6 phosphate amidotransferase 1; Hexosephosphate aminotransferase 1; MSLG;
Immunogens
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
- Q06210 GFPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q06210 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C2 | S-Nitrosylation | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| T149 | Phosphorylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| T201 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| K216 | Ubiquitination | Uniprot | |
| S235 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| S242 | Phosphorylation | Q13131 (PRKAA1) | Uniprot |
| K251 | Ubiquitination | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Q13131 (PRKAA1) , Q9UQM7 (CAMK2A) | Uniprot |
| T262 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| Y276 | Phosphorylation | Uniprot | |
| K345 | Ubiquitination | Uniprot | |
| Y367 | Phosphorylation | Uniprot | |
| T368 | Phosphorylation | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| T467 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| C478 | S-Nitrosylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| K547 | Acetylation | Uniprot | |
| K547 | Ubiquitination | Uniprot | |
| Y553 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| K650 | Acetylation | Uniprot | |
| K694 | Ubiquitination | Uniprot | |
| S695 | Phosphorylation | Uniprot |
Research Backgrounds
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
Homotetramer (Probable), may also exist as homodimers.
Research Fields
· Human Diseases > Endocrine and metabolic diseases > Insulin resistance.
· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.
· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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