TAF9B Antibody - #DF8206

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Product: TAF9B Antibody
Catalog: DF8206
Description: Rabbit polyclonal antibody to TAF9B
Application: WB
Reactivity: Human, Mouse
Prediction: Bovine, Horse, Sheep, Dog
Mol.Wt.: 28 kDa; 28kD(Calculated).
Uniprot: Q9HBM6
RRID: AB_2841514

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 100ul $280 In stock
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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
TAF9B Antibody detects endogenous levels of total TAF9B.
RRID:
AB_2841514
Cite Format: Affinity Biosciences Cat# DF8206, RRID:AB_2841514.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DN-7; DN7; Neuronal cell death related protein 7; Neuronal cell death-related protein 7; TAF9-like RNA polymerase II TBP associated factor, 31 kD; Taf9b; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAF9B_HUMAN; TAF9L; TAFII31L; TFIID-31; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9-like protein; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L;

Immunogens

Immunogen:
Uniprot:

Q9HBM6(TAF9B_HUMAN) >>Visit HPA database.

Gene(ID):
TAF9B(51616)
Sequence:
MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
63
Chicken
63
Pig
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9HBM6 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S3 Phosphorylation
K5 Ubiquitination
K10 Ubiquitination
K24 Ubiquitination
Y46 Phosphorylation
K55 Ubiquitination
Y57 Phosphorylation
K62 Ubiquitination
S82 Phosphorylation
S85 Phosphorylation
K99 Ubiquitination
T102 Phosphorylation
K108 Acetylation
K108 Ubiquitination
R119 Methylation
R128 Methylation
S147 Phosphorylation
S152 Phosphorylation
S153 Phosphorylation
T156 Phosphorylation
T157 Phosphorylation
T159 Phosphorylation
T162 Phosphorylation
T174 Phosphorylation
S177 Phosphorylation
S190 Phosphorylation
S192 Phosphorylation
T193 Phosphorylation

Research Backgrounds

Function:

Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Binds TAF5 and TAF6. Component of TFIID and the TATA-binding protein-free TAF complex (TFTC). TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Binds N-terminal domain of p53/TP53 which is essential for transcription.

Family&Domains:

Belongs to the TAF9 family.

Research Fields

· Genetic Information Processing > Transcription > Basal transcription factors.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

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