CDH4 Antibody - #DF8132
| Product: | CDH4 Antibody |
| Catalog: | DF8132 |
| Description: | Rabbit polyclonal antibody to CDH4 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| Mol.Wt.: | 140 kDa; 100kD(Calculated). |
| Uniprot: | P55283 |
| RRID: | AB_2841467 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8132, RRID:AB_2841467.
Fold/Unfold
CADH4_HUMAN; Cadherin 4; Cadherin-4; cdh4; R CAD; R-CAD; R-cadherin; Retinal cadherin;
Immunogens
- P55283 CADH4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P55283 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S60 | Phosphorylation | Uniprot | |
| T65 | Phosphorylation | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| T84 | O-Glycosylation | Uniprot | |
| T88 | O-Glycosylation | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| Y205 | Phosphorylation | Uniprot | |
| Y230 | Phosphorylation | Uniprot | |
| Y264 | Phosphorylation | Uniprot | |
| Y266 | Phosphorylation | Uniprot | |
| R405 | Methylation | Uniprot | |
| K546 | Ubiquitination | Uniprot | |
| K782 | Ubiquitination | Uniprot | |
| Y783 | Phosphorylation | Uniprot | |
| Y795 | Phosphorylation | Uniprot | |
| S798 | Phosphorylation | Uniprot | |
| S811 | Phosphorylation | Uniprot |
Research Backgrounds
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.
Cell membrane>Single-pass type I membrane protein.
Expressed mainly in brain but also found in other tissues.
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
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