FDX1 Antibody - #DF7950
| Product: | FDX1 Antibody |
| Catalog: | DF7950 |
| Description: | Rabbit polyclonal antibody to FDX1 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 19 kDa; 19kD(Calculated). |
| Uniprot: | P10109 |
| RRID: | AB_2841351 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF7950, RRID:AB_2841351.
Fold/Unfold
Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial;
Immunogens
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
- P10109 ADX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAGGARLLRAASAVLGGPAGRWLHHAGSRAGSSGLLRNRGPGGSAEASRSLSVSARARSSSEDKITVHFINRDGETLTTKGKVGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAYGLTDRSRLGCQICLTKSMDNMTVRVPETVADARQSIDVGKTS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P10109 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S35 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| T68 | Phosphorylation | Uniprot | |
| T131 | Phosphorylation | Uniprot | |
| R149 | Methylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot |
Research Backgrounds
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
Mitochondrion matrix.
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Interacts with CYP11A1.
Belongs to the adrenodoxin/putidaredoxin family.
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