CD2 Antibody - #DF7894
| Product: | CD2 Antibody |
| Catalog: | DF7894 |
| Description: | Rabbit polyclonal antibody to CD2 |
| Application: | WB |
| Reactivity: | Human |
| Mol.Wt.: | 39 kDa; 39kD(Calculated). |
| Uniprot: | P06729 |
| RRID: | AB_2841315 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF7894, RRID:AB_2841315.
Fold/Unfold
CD 2; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2_HUMAN; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor; Ly-37; Lymphocyte function antigen 2; lymphocyte-function antigen-2; OTTHUMP00000024366; Rosette receptor; Sheep erythrocyte receptor; SRBC; T cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-lymphocyte surface CD2 antigen; T11;
Immunogens
- P06729 CD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
PTMs - P06729 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N89 | N-Glycosylation | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| N141 | N-Glycosylation | Uniprot | |
| N150 | N-Glycosylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| T173 | Phosphorylation | Uniprot | |
| T258 | Phosphorylation | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K324 | Ubiquitination | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S350 | Phosphorylation | Uniprot |
Research Backgrounds
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Cell membrane>Single-pass type I membrane protein.
Interacts with CD48 (By similarity). Interacts with CD58 (LFA-3). Interacts with CD2AP (By similarity). Interacts with PSTPIP1.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
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