Product: SULT1A3 Antibody
Catalog: DF7889
Description: Rabbit polyclonal antibody to SULT1A3
Application: WB IHC
Reactivity: Human
Mol.Wt.: 34 kDa; 34kD(Calculated).
Uniprot: P0DMN0
RRID: AB_2841310

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
SULT1A3 Antibody detects endogenous levels of total SULT1A3.
RRID:
AB_2841310
Cite Format: Affinity Biosciences Cat# DF7889, RRID:AB_2841310.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P0DMN0 ST1A4_HUMAN:

Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

Sequence:
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

PTMs - P0DMN0 As Substrate

Site PTM Type Enzyme
K16 Ubiquitination
K97 Ubiquitination
K106 Ubiquitination
K122 Ubiquitination
K124 Ubiquitination
S253 Phosphorylation
K283 Ubiquitination

Research Backgrounds

Function:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

PTMs:

The N-terminus is blocked.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the sulfotransferase 1 family.

Research Fields

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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