GTPBP4 Antibody - #DF7875

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Product: GTPBP4 Antibody
Catalog: DF7875
Description: Rabbit polyclonal antibody to GTPBP4
Application: WB
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken
Mol.Wt.: 74 kDa; 74kD(Calculated).
Uniprot: Q9BZE4
RRID: AB_2841303

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(90%), Horse(100%), Sheep(90%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
GTPBP4 Antibody detects endogenous levels of total GTPBP4.
RRID:
AB_2841303
Cite Format: Affinity Biosciences Cat# DF7875, RRID:AB_2841303.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Chronic renal failure gene protein; CRFG; G protein binding protein CRFG; GTP binding protein 4; GTP-binding protein NGB; Gtpbp4; NGB; NOG1; NOG1_HUMAN; Nucleolar GTP binding protein 1; Nucleolar GTP-binding protein 1;

Immunogens

Immunogen:
Uniprot:

Q9BZE4(NOG1_HUMAN) >>Visit HPA database.

Gene(ID):
GTPBP4(23560)
Sequence:
MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDLELEMGDDYILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEKEEELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEKNTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYAVQARRSRSITRKRKREDSAPPSSVARSGSCSRTPRDVSGLRDVKMVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Chicken
100
Bovine
90
Sheep
90
Xenopus
70
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BZE4 As Substrate

Site PTM Type Enzyme
K7 Acetylation
K8 Sumoylation
K8 Ubiquitination
K16 Ubiquitination
S24 Phosphorylation
K25 Ubiquitination
K29 Ubiquitination
T30 Phosphorylation
K36 Acetylation
R61 Methylation
S63 Phosphorylation
K93 Ubiquitination
K103 Acetylation
K103 Ubiquitination
K111 Ubiquitination
K118 Acetylation
K118 Ubiquitination
S122 Phosphorylation
K127 Ubiquitination
K142 Ubiquitination
K145 Ubiquitination
Y150 Phosphorylation
T163 Phosphorylation
T168 Phosphorylation
K181 Sumoylation
K181 Ubiquitination
K187 Ubiquitination
K203 Ubiquitination
K213 Acetylation
K213 Ubiquitination
R233 Methylation
K282 Ubiquitination
S300 Phosphorylation
K305 Sumoylation
K305 Ubiquitination
K332 Sumoylation
R338 Methylation
K347 Ubiquitination
K352 Sumoylation
K352 Ubiquitination
K371 Ubiquitination
Y409 Phosphorylation
K425 Ubiquitination
K428 Ubiquitination
Y441 Phosphorylation
K448 Ubiquitination
K449 Sumoylation
K449 Ubiquitination
T461 Phosphorylation
Y466 Phosphorylation
S468 Phosphorylation
S470 Phosphorylation
S472 Phosphorylation
K494 Sumoylation
K494 Ubiquitination
K513 Methylation
K522 Acetylation
K522 Ubiquitination
K534 Sumoylation
Y539 Phosphorylation
S558 Phosphorylation
S562 Phosphorylation
S563 Phosphorylation
S578 Phosphorylation
R581 Methylation
K584 Sumoylation
K619 Ubiquitination
S623 Phosphorylation
K625 Acetylation

Research Backgrounds

Function:

Involved in the biogenesis of the 60S ribosomal subunit.

Subcellular Location:

Nucleus>Nucleolus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.

Research Fields

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

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