TAS2R38 Antibody | Affinity Biosciences

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Western blot analysis of TAS2R38 using COLO205 whole cell lysates.

Product:	TAS2R38 Antibody
Catalog:	DF10267
Description:	Rabbit polyclonal antibody to TAS2R38
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Sheep
Mol.Wt.:	38 kDa; 38kD(Calculated).
Uniprot:	P59533
RRID:	AB_2840845

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(89%), Sheep(89%)

Clonality:

Polyclonal

Specificity:

TAS2R38 Antibody detects endogenous levels of total TAS2R38.

RRID:

AB_2840845
Cite Format: Affinity Biosciences Cat# DF10267, RRID:AB_2840845.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

PTC; PTC bitter taste receptor; T2R38; T2R38_HUMAN; T2R61; TAS2R38; Taste receptor type 2 member 38; Taste receptor type 2 member 61; taste receptor, type 2, member 38;

Immunogens

Immunogen:

Uniprot:

P59533(T2R38_HUMAN) >>Visit HPA database.

Gene(ID):

TAS2R38(5726)

Expression:

P59533 T2R38_HUMAN:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis (PubMed:16720576).

Sequence:

P59533 T2R38_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLEAHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Pig

Sheep

Horse

Bovine

Dog

Xenopus

Zebrafish

Chicken

Rabbit

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P59533 As Substrate

P59533

Site	PTM Type	Enzyme	Source
T5	Phosphorylation		Uniprot
S291	Phosphorylation		Uniprot

Research Backgrounds

P59533_T2R38_HUMAN

Function:

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

Subcellular Location:

Membrane>Multi-pass membrane protein.

Tissue Specificity:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis.

Family&Domains:

Belongs to the G-protein coupled receptor T2R family.

Research Fields

· Organismal Systems > Sensory system > Taste transduction.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

TAS2R38 Antibody - #DF10267