P2RY2 Antibody - #DF10259
| Product: | P2RY2 Antibody |
| Catalog: | DF10259 |
| Description: | Rabbit polyclonal antibody to P2RY2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Horse, Dog |
| Mol.Wt.: | 42 kDa; 42kD(Calculated). |
| Uniprot: | P41231 |
| RRID: | AB_2840837 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10259, RRID:AB_2840837.
Fold/Unfold
ATP receptor; HP2U; Human P2U nucleotide receptor mRNA complete cds; MGC20088; MGC40010; P2RU1; P2ry2; P2RY2_HUMAN; P2U; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; Purinergic receptor; Purinergic receptor P2Y G protein coupled 2; Purinergic receptor P2Y2; Purinoceptor P2Y2;
Immunogens
- P41231 P2RY2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P41231 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K227 | Ubiquitination | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| T324 | Phosphorylation | Uniprot | |
| S327 | Phosphorylation | Uniprot | |
| T330 | Phosphorylation | Uniprot | |
| T344 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S369 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.
Cell membrane>Multi-pass membrane protein.
Spleen, testis, kidney, liver, lung, heart and brain.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Sensory system > Inflammatory mediator regulation of TRP channels. (View pathway)
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