Product: CCR8 Antibody
Catalog: DF10208
Description: Rabbit polyclonal antibody to CCR8
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Horse
Mol.Wt.: 41 kDa, 50 kDa; 41kD(Calculated).
Uniprot: P51685
RRID: AB_2840787

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Horse(100%)
Clonality:
Polyclonal
Specificity:
CCR8 Antibody detects endogenous levels of total CCR8.
RRID:
AB_2840787
Cite Format: Affinity Biosciences Cat# DF10208, RRID:AB_2840787.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C C chemokine receptor type 8; C C CKR 8; C C motif chemokine receptor 8; C-C chemokine receptor type 8; C-C CKR-8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC chemokine receptor type 8; CC CKR 8; CC-CKR-8; CCR 8; CCR-8; Ccr8; CCR8 protein; CCR8-L; CCR8_HUMAN; CDw198; CDw198 antigen; Chemokine (C C motif) receptor 8; Chemokine (C C) receptor 8; Chemokine (C C) receptor like 2; Chemokine (CC motif) receptor 8; Chemokine (CC) receptor 8; Chemokine (CC) receptor like 1; Chemokine (CC) receptor like 2; Chemokine C C motif receptor 8; Chemokine C C receptor 8; Chemokine CC motif receptor 8; Chemokine CC receptor 8; Chemokine receptor 8; Chemokine receptor like 1; Chemokine receptor-like 1; CKR L1; CKR-L1; CKRL 1; CKRL1; CMKBR 8; CMKBR L2; CMKBR8; CMKBRL 2; CMKBRL2; CY 6; CY6; GPR CY6; GPR-CY6; GPRCY6; MGC123958; MGC123959; MGC129966; MGC129973; TER 1; TER1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
63
Bovine
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P51685 As Substrate

Site PTM Type Enzyme
Y132 Phosphorylation
S334 Phosphorylation
S338 Phosphorylation
S339 Phosphorylation
S340 Phosphorylation

Research Backgrounds

Function:

Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Human Diseases > Cancers: Overview > Viral carcinogenesis.

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.