TNFRSF17 Antibody - #DF10193
Product: | TNFRSF17 Antibody |
Catalog: | DF10193 |
Description: | Rabbit polyclonal antibody to TNFRSF17 |
Application: | WB IF/ICC |
Reactivity: | Human, Rat |
Prediction: | Horse, Dog |
Mol.Wt.: | 20 kDa; 20kD(Calculated). |
Uniprot: | Q02223 |
RRID: | AB_2840772 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10193, RRID:AB_2840772.
Fold/Unfold
B cell maturation antigen; B cell maturation factor; B cell maturation protein; B-cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; TNR17_HUMAN; Tumor necrosis factor receptor superfamily member 17;
Immunogens
- Q02223 TNR17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEIILPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAALSATEIEKSISAR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02223 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K86 | Acetylation | Uniprot | |
K86 | Ubiquitination | Uniprot | |
K106 | Acetylation | Uniprot | |
K106 | Ubiquitination | Uniprot | |
Y121 | Phosphorylation | Uniprot | |
K133 | Ubiquitination | Uniprot | |
K135 | Ubiquitination | Uniprot | |
K137 | Ubiquitination | Uniprot | |
K160 | Ubiquitination | Uniprot | |
K166 | Ubiquitination | Uniprot | |
S173 | Phosphorylation | Uniprot | |
K179 | Ubiquitination | Uniprot |
Research Backgrounds
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Cell membrane>Single-pass type III membrane protein. Endomembrane system>Single-pass type III membrane protein.
Note: Perinuclear Golgi-like structures.
Expressed in mature B-cells, but not in T-cells or monocytes.
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
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