REG4 Antibody - #DF10183
| Product: | REG4 Antibody |
| Catalog: | DF10183 |
| Description: | Rabbit polyclonal antibody to REG4 |
| Application: | WB |
| Reactivity: | Human |
| Mol.Wt.: | 18 kDa; 18kD(Calculated). |
| Uniprot: | Q9BYZ8 |
| RRID: | AB_2840762 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10183, RRID:AB_2840762.
Fold/Unfold
Gastrointestinal secretory protein; GISP; Reg IV; REG like protein; REG-4; REG-like protein; Reg4; REG4_HUMAN; Regenerating gene type IV; Regenerating islet derived family member 4; Regenerating islet derived protein 4 precursor; Regenerating islet-derived protein 4; Regenerating islet-derived protein IV; REGIV; RELP;
Immunogens
Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
- Q9BYZ8 REG4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP
PTMs - Q9BYZ8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| Y82 | Phosphorylation | Uniprot |
Research Backgrounds
Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
Secreted.
Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
Research Fields
· Human Diseases > Cancers: Specific types > Gastric cancer. (View pathway)
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