RLN3 Antibody - #DF10177

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Product: RLN3 Antibody
Catalog: DF10177
Description: Rabbit polyclonal antibody to RLN3
Application: WB IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Sheep, Rabbit
Mol.Wt.: 15 kDa; 15kD(Calculated).
Uniprot: Q8WXF3
RRID: AB_2840756

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(86%), Bovine(100%), Sheep(83%), Rabbit(86%)
Clonality:
Polyclonal
Specificity:
RLN3 Antibody detects endogenous levels of total RLN3.
RRID:
AB_2840756
Cite Format: Affinity Biosciences Cat# DF10177, RRID:AB_2840756.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

H3; INSL 7; INSL7; Insulin like 7; Insulin like peptide 7; Insulin like peptide INSL7; Insulin like7; Insulinlike 7; Prorelaxin H3; Prorelaxin M3; REL 3; REL3; Relaxin 3; Relaxin 3 (H3); Relaxin 3 A chain; Relaxin 3 B chain; Relaxin 3 precursor; Relaxin3; RLN 3; RLN3; RXN 3; RXN3; ZINS 4; ZINS4;

Immunogens

Immunogen:
Uniprot:

Q8WXF3(REL3_HUMAN) >>Visit HPA database.

Gene(ID):
RLN3(117579)
Sequence:
MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAHEAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDVLAGLSSSCCKWGCSKSEISSLC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Pig
86
Rabbit
86
Sheep
83
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8WXF3 As Substrate

Site PTM Type Enzyme
Y30 Phosphorylation

Research Backgrounds

Function:

May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Family&Domains:

Belongs to the insulin family.

Research Fields

· Organismal Systems > Endocrine system > Relaxin signaling pathway.

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Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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