Product: CDC37L1 Antibody
Catalog: DF10175
Description: Rabbit polyclonal antibody to CDC37L1
Application: WB IHC IF/ICC
Reactivity: Human, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 39 kDa; 39kD(Calculated).
Uniprot: Q7L3B6
RRID: AB_2840754

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(92%), Xenopus(92%)
Clonality:
Polyclonal
Specificity:
CDC37L1 Antibody detects endogenous levels of total CDC37L1.
RRID:
AB_2840754
Cite Format: Affinity Biosciences Cat# DF10175, RRID:AB_2840754.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CD37L_HUMAN; CDC37 cell division cycle 37 homolog like 1; CDC37-like 1; CDC37B; Cdc37l; Cdc37l1; Cell division cycle 37 homolog (S. cerevisiae) like 1; Cell division cycle 37, S. cerevisiae, homolog-like 1; FLJ20639; HARC; Hsp90 associating relative of Cdc37; Hsp90 co-chaperone Cdc37-like 1; Hsp90-associating relative of Cdc37; RP11-6J24.5;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q7L3B6 CD37L_HUMAN:

Expressed in brain, heart, kidney, liver, placenta and skeletal muscle.

Sequence:
MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQREKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
92
Chicken
92
Zebrafish
58
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q7L3B6 As Substrate

Site PTM Type Enzyme
S31 Phosphorylation
S32 Phosphorylation
K62 Methylation
K62 Ubiquitination
K77 Ubiquitination
S88 Phosphorylation
K95 Ubiquitination
T98 Phosphorylation
S101 Phosphorylation
K113 Ubiquitination
K138 Ubiquitination
K260 Ubiquitination

Research Backgrounds

Function:

Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain, heart, kidney, liver, placenta and skeletal muscle.

Subunit Structure:

Self-associates. Forms complexes with Hsp70 and Hsp90. Interacts with CDC37, FKBP4, PPID and STIP1.

Family&Domains:

Belongs to the CDC37 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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