PSD4 Antibody - #DF10161

(1)  
Product: PSD4 Antibody
Catalog: DF10161
Description: Rabbit polyclonal antibody to PSD4
Application: WB
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 116kDa; 116kD(Calculated).
Uniprot: Q8NDX1
RRID: AB_2840740

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
PSD4 Antibody detects endogenous levels of total PSD4.
RRID:
AB_2840740
Cite Format: Affinity Biosciences Cat# DF10161, RRID:AB_2840740.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4; PSD4; PSD4_HUMAN; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC;

Immunogens

Immunogen:
Uniprot:

Q8NDX1(PSD4_HUMAN) >>Visit HPA database.

Gene(ID):
PSD4(23550)
Expression:
Q8NDX1 PSD4_HUMAN:

Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

Sequence:
MMGDYRLPDHPQPMEILNLYLGDSLEPHPGECPRETCSHEDPPEPFEEQTWATDPPEPTRQNVPPWGSGVELTHLGSWVHQDGLEPCQEQTRATDPPESTRQDAPPWGSGVELTHLGSPSAQREHRQNTASPGSPVNSHLPGSPKQNRSTSTQVVFWAGILQAQMCVLDLEEELEKTEGLKAGLKCCLPTPPVDLPGDTGLHSSPPENEDSGEDSSEPEGEGQAWLREGTPDSSPQWGAEEESMFFSNPLFLASPCSENSASGECFSWGASDSHAGVRTGPESPATLEPPLPEDTVLWELESEPDLGDGAAISGHCTPPFPVPIYKPHSICWASVAAAEGAPAAPPGHGESEGDRLGPAPSAAPCVDEALTWESGCVGSDLGPAAHPVQPWASLSPEGWQRGGPFWPQVTLNSQDRDEREGGHPQESLPCTLAPCPWRSPASSPEPSSPESESRGPGPRPSPASSQEGSPQLQHHSSGILPKWTLDASQSSLLETDGEQPSSLKKKEAGEAPKPGEEVKSEGTARPAETGDVQPDIHLTSAEHENLRTPMNSSWLPGSPMPQAQSPEEGQRPPAGDKLANGVRNNKVAWNLASRLYRLEGFRKSEVAAYLQKNNDFSRAVAEEYLSFFQFGGQSLDRALRSFLQALVLSGETQERERILYQFSRRFHHCNPGIFPSVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFITNLNGLRDGGNFPKELLKALYWSIRSEKLEWAVDEEDTARPEKAQPSLPAGKMSKPFLQLAQDPTVPTYKQGILARKMHQDADGKKTPWGKRGWKMFHTLLRGMVLYFLKQGEDHCLEGESLVGQMVDEPVGVHHSLATPATHYTKKPHVFQLRTADWRLYLFQAPTAKEMSSWIARINLAAATHSAPPFPAAVGSQRRFVRPILPVGPAQSSLEEQHRSHENCLDAAADDLLDLQRNLPERRGRGRELEEHRLRKEYLEYEKTRYETYVQLLVARLHCPSDALDLWEEQLGREAGGTREPKLSLKKSHSSPSLHQDEAPTTAKVKRNISERRTYRKIIPKRNRNQL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NDX1 As Substrate

Site PTM Type Enzyme
T50 Phosphorylation
S68 Phosphorylation
S77 Phosphorylation
S109 Phosphorylation
T114 Phosphorylation
S118 Phosphorylation
S131 Phosphorylation
S134 Phosphorylation
S138 Phosphorylation
S143 Phosphorylation
K181 Ubiquitination
T230 Phosphorylation
S233 Phosphorylation
T317 Phosphorylation
S395 Phosphorylation
T410 Phosphorylation
S413 Phosphorylation
S448 Phosphorylation
S461 Phosphorylation
S464 Phosphorylation
S465 Phosphorylation
S469 Phosphorylation
S488 Phosphorylation
S490 Phosphorylation
S491 Phosphorylation
T495 Phosphorylation
S501 Phosphorylation
S502 Phosphorylation
T548 Phosphorylation
S558 Phosphorylation
S565 Phosphorylation
K586 Ubiquitination
K603 Ubiquitination
K723 Ubiquitination
K752 Ubiquitination
K761 Ubiquitination
S763 Phosphorylation
K764 Ubiquitination
K779 Ubiquitination
K786 Ubiquitination
T808 Phosphorylation
Y816 Phosphorylation
S905 Phosphorylation
Y975 Phosphorylation
S1013 Phosphorylation
K1016 Ubiquitination
S1017 Phosphorylation
S1019 Phosphorylation
S1020 Phosphorylation
S1022 Phosphorylation
T1031 Phosphorylation
S1039 Phosphorylation
T1043 Phosphorylation
K1046 Ubiquitination

Research Backgrounds

Function:

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

Subcellular Location:

Cell membrane. Cell projection>Ruffle membrane.
Note: In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394). Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148). Recruited to membranes via phosphatidylinositol phosphate-binding (Probable).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

Research Fields

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.