Cytochrome P450 4Z1/2 Antibody - #DF10128
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10128, RRID:AB_2840708.
Fold/Unfold
CP4Z1_HUMAN; CYP4A20; CYP4Z1; CYPIVZ1; Cytochrome P450 4Z1; Cytochrome P450 family 4 subfamily Z polypeptide 1; CP4Z2_HUMAN;CYP4Z2P;Putative inactive cytochrome P450 family member 4Z2;
Immunogens
Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.
Q8N1L4 CP4Z2_HUMAN:Detected at low levels in mammary gland and mammary carcinoma.
- Q86W10 CP4Z1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKVC
- Q8N1L4 CP4Z2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFEVYPELMEKYPCAVPLWVGPFTMFFNIHDPDYVKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRQDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTTTAISWIFYCLAKYPEHQQRC
PTMs - Q86W10/Q8N1L4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y55 | Phosphorylation | Uniprot | |
| T154 | Phosphorylation | Uniprot | |
| Y376 | Phosphorylation | Uniprot | |
| K492 | Ubiquitination | Uniprot |
Research Backgrounds
Endoplasmic reticulum membrane>Single-pass type II membrane protein. Microsome membrane>Single-pass type II membrane protein.
Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.
Belongs to the cytochrome P450 family.
Membrane>Single-pass type II membrane protein.
Detected at low levels in mammary gland and mammary carcinoma.
Belongs to the cytochrome P450 family.
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