POLM Antibody - #DF10080
| Product: | POLM Antibody |
| Catalog: | DF10080 |
| Description: | Rabbit polyclonal antibody to POLM |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Zebrafish, Horse, Sheep, Rabbit |
| Mol.Wt.: | 55 kDa; 55kD(Calculated). |
| Uniprot: | Q9NP87 |
| RRID: | AB_2840660 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10080, RRID:AB_2840660.
Fold/Unfold
DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase;
Immunogens
- Q9NP87 DPOLM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVECRHRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCCESPTRLAQQSHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NP87 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| T21 | Phosphorylation | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| K339 | Ubiquitination | Uniprot | |
| S372 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K452 | Ubiquitination | Uniprot | |
| K467 | Ubiquitination | Uniprot |
Research Backgrounds
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
Nucleus.
Expressed in a number of tissues. Abundant in thymus.
Belongs to the DNA polymerase type-X family.
Research Fields
· Genetic Information Processing > Replication and repair > Non-homologous end-joining.
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