ATP6V1B2 Antibody - #DF10004
| Product: | ATP6V1B2 Antibody |
| Catalog: | DF10004 |
| Description: | Rabbit polyclonal antibody to ATP6V1B2 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 57 kDa; 57kD(Calculated). |
| Uniprot: | P21281 |
| RRID: | AB_2840584 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10004, RRID:AB_2840584.
Fold/Unfold
ATP6B1B2; ATP6B2; ATP6V1 B2; ATP6V1B 2; ATP6V1B2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B isoform 2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B2; ATPase H+ transporting, lysosomal (vacuolar proton pump) beta polypeptide 56/58kD isoform 2; ATPase, H+ transporting, lysosomal V1 subunit B2; brain isoform; Endomembrane proton pump 58 kDa subunit; H+ transporting two sector ATPase; HO 57; HO57; V ATPase B2 subunit; V ATPase subunit B 2; V type proton ATPase subunit B, brain isoform; V-ATPase subunit B 2; V-type proton ATPase subunit B; Vacuolar ATP synthase subunit B brain isoform; Vacuolar H+ ATPase 56,000 subunit; Vacuolar H+ ATPase 56000 subunit; Vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2; VAT B2; VATB 2; VATB; VATB2; VATB2_HUMAN; Vma 2; Vma2; VPP 3; VPP3;
Immunogens
- P21281 VATB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P21281 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R4 | Methylation | Uniprot | |
| R7 | Methylation | Uniprot | |
| Y39 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| R44 | Methylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| R67 | Methylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K108 | Acetylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| C112 | S-Nitrosylation | Uniprot | |
| S124 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| S182 | Phosphorylation | Uniprot | |
| R185 | Methylation | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| Y222 | Phosphorylation | Uniprot | |
| Y328 | Phosphorylation | Uniprot | |
| Y389 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| K403 | Ubiquitination | Uniprot | |
| K457 | Ubiquitination | Uniprot | |
| R460 | Methylation | Uniprot | |
| R506 | Methylation | Uniprot |
Research Backgrounds
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Endomembrane system>Peripheral membrane protein. Melanosome.
Note: Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).
Belongs to the ATPase alpha/beta chains family.
Research Fields
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.
· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.
· Human Diseases > Immune diseases > Rheumatoid arthritis.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Synaptic vesicle cycle.
· Organismal Systems > Excretory system > Collecting duct acid secretion.
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