Product: C1orf57 Antibody
Catalog: AF0448
Description: Rabbit polyclonal antibody to C1orf57
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 21kDa; 21kD(Calculated).
Uniprot: Q9BSD7
RRID: AB_2834309

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(92%), Horse(92%), Sheep(92%), Rabbit(92%)
Clonality:
Polyclonal
Specificity:
C1orf57 Antibody detects endogenous levels of total C1orf57.
RRID:
AB_2834309
Cite Format: Affinity Biosciences Cat# AF0448, RRID:AB_2834309.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Chromosome 1 open reading frame 57; FLJ11383; HCR NTPase; Human cancer related NTPase; Hypothetical protein LOC84284; MGC13186; Novel DUF829 domain containing protein; Nucleoside triphosphatase C1orf57; Nucleoside triphosphatase, cancer related; Nucleoside triphosphate phosphohydrolase; OTTHUMP00000035941; OTTHUMP00000035942; Probable UPF0334 kinase like protein C1orf57; RP4 659I19.2; RP4 678E16.2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Description:
C1orf57 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency. Belongs to the THEP1 NTPase family. Monomer.
Sequence:
MARHVFLTGPPGVGKTTLIHKASEVLKSSGVPVDGFYTEEVRQGGRRIGFDVVTLSGTRGPLSRVGLEPPPGKRECRVGQYVVDLTSFEQLALPVLRNADCSSGPGQRVCVIDEIGKMELFSQLFIQAVRQTLSTPGTIILGTIPVPKGKPLALVEEIRNRKDVKVFNVTKENRNHLLPDIVTCVQSSRK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
92
Bovine
92
Sheep
92
Rabbit
92
Pig
75
Zebrafish
70
Chicken
67
Dog
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BSD7 As Substrate

Site PTM Type Enzyme
A2 Acetylation
T8 Phosphorylation
K15 Ubiquitination
K21 Acetylation
K21 Ubiquitination
K27 Ubiquitination
Y37 Phosphorylation
T38 Phosphorylation
T54 Phosphorylation
S56 Phosphorylation
K73 Ubiquitination
K150 Ubiquitination
K165 Acetylation
K165 Ubiquitination
T170 Phosphorylation
K171 Ubiquitination

Research Backgrounds

Function:

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the THEP1 NTPase family.

Research Fields

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Thiamine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.