Product: Phospho-KIF1C (Ser1092) Antibody
Catalog: AF8091
Description: Rabbit polyclonal antibody to Phospho-KIF1C (Ser1092)
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 120~150kD; 123kD(Calculated).
Uniprot: O43896
RRID: AB_2840154

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 100ul $350 In stock
 200ul $450 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
Phospho-KIF1C (Ser1092) Antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
RRID:
AB_2840154
Cite Format: Affinity Biosciences Cat# AF8091, RRID:AB_2840154.
Conjugate:
Unconjugated.
Purification:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Kif1c; KIF1C_HUMAN; Kinesin family member 1C; Kinesin-like protein KIF1C; LTXS1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O43896 KIF1C_HUMAN:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

Sequence:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDMDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDRMPSARPPSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDLKESGAAV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O43896 As Substrate

Site PTM Type Enzyme
S162 Phosphorylation
T222 Phosphorylation
K243 Ubiquitination
S257 Phosphorylation
S258 Phosphorylation
K266 Ubiquitination
S274 Phosphorylation
T276 Phosphorylation
T277 Phosphorylation
S295 Phosphorylation
S326 Phosphorylation
Y332 Phosphorylation
S385 Phosphorylation
S412 Phosphorylation
T489 Phosphorylation
S494 Phosphorylation
K658 Ubiquitination
Y671 Phosphorylation
S674 Phosphorylation
S676 Phosphorylation
S680 Phosphorylation
T702 Phosphorylation
T703 Phosphorylation
Y726 Phosphorylation
K788 Ubiquitination
S817 Phosphorylation
K839 Ubiquitination
K848 Ubiquitination
S915 Phosphorylation
S919 Phosphorylation
R948 Methylation
S955 Phosphorylation
R958 Methylation
R963 Methylation
S996 Phosphorylation
S1022 Phosphorylation
S1033 Phosphorylation
R1041 Methylation
K1057 Methylation
R1072 Methylation
R1077 Methylation
Y1078 Phosphorylation
Y1081 Phosphorylation
T1082 Phosphorylation
T1083 Phosphorylation
S1092 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2)

Research Backgrounds

Function:

Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.

PTMs:

Phosphorylated on tyrosine residues.

Subcellular Location:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

Subunit Structure:

Monomer. Interacts with BICD2.

Family&Domains:

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

Restrictive clause

 

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For Research Use Only.
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