MAOA Mouse Monoclonal Antibody | Affinity Biosciences

Product:	MAOA Mouse Monoclonal Antibody
Catalog:	BF8520
Description:	Mouse monoclonal antibody to MAOA
Application:	WB
Reactivity:	Human
Prediction:	Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.:	60~70 kD; 60kD(Calculated).
Uniprot:	P21397

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Local distributors

Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Monoclonal [AFfirm8520]

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

Amine oxidase [flavin containing] A; Amine oxidase [flavin-containing] A; AOFA; AOFA_HUMAN; EC 1.4.3.4; MAO A; MAO-A; maoA; Monoamine oxidase A; Monoamine oxidase type A;

Immunogens

Immunogen:

Uniprot:

P21397(AOFA_HUMAN) >>Visit HPA database.

Gene(ID):

MAOA(4128)

Expression:

P21397 AOFA_HUMAN:

Heart, liver, duodenum, blood vessels and kidney.

Description:

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Sequence:

P21397 AOFA_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS

PTMs - P21397 As Substrate

P21397

Site	PTM Type	Enzyme	Source
M1	Acetylation		Uniprot
T52	Phosphorylation		Uniprot
Y53	Phosphorylation		Uniprot
K136	Acetylation		Uniprot
S209	Phosphorylation	Q16539 (MAPK14)	Uniprot
K218	Ubiquitination		Uniprot
Y268	Phosphorylation		Uniprot
S345	Phosphorylation		Uniprot
S383	Phosphorylation		Uniprot
K469	Ubiquitination		Uniprot

Research Backgrounds

P21397_AOFA_HUMAN

Function:

Subcellular Location:

Mitochondrion outer membrane>Single-pass type IV membrane protein>Cytoplasmic side.

Tissue Specificity:

Heart, liver, duodenum, blood vessels and kidney.

Subunit Structure:

Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

Family&Domains:

Belongs to the flavin monoamine oxidase family.

Research Fields

· Human Diseases > Substance dependence > Cocaine addiction.

· Human Diseases > Substance dependence > Amphetamine addiction.

· Human Diseases > Substance dependence > Alcoholism.

· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.

· Metabolism > Amino acid metabolism > Arginine and proline metabolism.

· Metabolism > Amino acid metabolism > Histidine metabolism.

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Amino acid metabolism > Phenylalanine metabolism.

· Metabolism > Amino acid metabolism > Tryptophan metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Serotonergic synapse.

· Organismal Systems > Nervous system > Dopaminergic synapse.

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AFfirm™ MAOA Mouse Monoclonal Antibody - #BF8520