Transferrin antibody - #BF0720

(1)  
Product: Transferrin antibody
Catalog: BF0720
Description: Mouse monoclonal antibody to Transferrin
Application: WB
Reactivity: Human
Mol.Wt.: 77kDa; 77kD(Calculated).
Uniprot: P02787
RRID: AB_2846196

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MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB(1:1000-1:10000)
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFB17783]
Specificity:
Transferrin mouse monoclonal antibody detects endogenous levels of total Transferrin.
RRID:
AB_2846196
Cite Format: Affinity Biosciences Cat# BF0720, RRID:AB_2846196.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Apotransferrin;Beta 1 metal binding globulin;Beta-1 metal-binding globulin;DKFZp781D0156;PRO1400;PRO1557;PRO2086;Serotransferrin;Serotransferrin precursor;Siderophilin;TF;TFQTL1;Transferin;Transferrin;TRFE_HUMAN;

Immunogens

Immunogen:

Purified recombinant fragment of human Trasnferrin expressed in E. Coli.

Uniprot:

P02787(TRFE_HUMAN) >>Visit HPA database.

Gene(ID):
TF(7018)
Expression:
P02787 TRFE_HUMAN:

Expressed by the liver and secreted in plasma.

Sequence:
MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP

PTMs - P02787 As Substrate

Site PTM Type Enzyme
T36 Phosphorylation
K37 Acetylation
C58 S-Nitrosylation
S63 Phosphorylation
Y64 Phosphorylation
S136 Phosphorylation
C137 S-Nitrosylation
T139 Phosphorylation
S144 Phosphorylation
Y155 Phosphorylation
Y207 Phosphorylation
C213 S-Nitrosylation
C246 S-Nitrosylation
Y257 Phosphorylation
C260 S-Nitrosylation
S298 Phosphorylation
S305 Phosphorylation
S306 Phosphorylation
T340 Phosphorylation
T349 Phosphorylation
T355 Phosphorylation
K359 Acetylation
C364 S-Nitrosylation
C374 S-Nitrosylation
S389 Phosphorylation
C396 S-Nitrosylation
S468 Phosphorylation
T476 Phosphorylation
N491 N-Glycosylation
C503 S-Nitrosylation
K508 Acetylation
S520 Phosphorylation
C525 S-Nitrosylation
Y533 Phosphorylation
Y534 Phosphorylation
Y536 Phosphorylation
T537 Phosphorylation
K546 Acetylation
C582 S-Nitrosylation
Y593 Phosphorylation
C596 S-Nitrosylation
T645 Phosphorylation
T654 Phosphorylation
Y666 Phosphorylation
Y669 Phosphorylation
Y674 Phosphorylation
C684 S-Nitrosylation
S685 Phosphorylation
T686 Phosphorylation
S688 Phosphorylation
T694 Phosphorylation

Research Backgrounds

Function:

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed by the liver and secreted in plasma.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the transferrin family.

Research Fields

· Cellular Processes > Cell growth and death > Ferroptosis.   (View pathway)

· Environmental Information Processing > Signal transduction > HIF-1 signaling pathway.   (View pathway)

· Organismal Systems > Digestive system > Mineral absorption.

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