TGF beta Receptor III Antibody - #BF2002

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Product: TGF beta Receptor III Antibody
Catalog: BF2002
Description: Mouse monoclonal antibody to TGF beta Receptor III
Application: WB ELISA FACS
Reactivity: Human, Mouse
Mol.Wt.: 93.4kDa; 93kD(Calculated).
Uniprot: Q03167
RRID: AB_2837576

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Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Monoclonal [AFB5590]
RRID:
AB_2837576
Cite Format: Affinity Biosciences Cat# BF2002, RRID:AB_2837576.
Conjugate:
Unconjugated.
Purification:
affinity purification.
Storage:
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.Store at -20°C. Stable for one year from the date of shipment. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Beta glycan; Betaglycan; Betaglycan proteoglycan; BGCAN; TGBR3_HUMAN; TGF beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type 3; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming growth factor beta receptor III; Transforming growth factor beta receptor III betaglycan 300kDa; Transforming growth factor beta receptor type 3;

PTMs - Q03167 As Substrate

Site PTM Type Enzyme
T84 Phosphorylation
T369 O-Glycosylation
K667 Ubiquitination
S831 Phosphorylation P36897 (TGFBR1)
T843 Phosphorylation P37173 (TGFBR2)

Research Backgrounds

Function:

Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.

PTMs:

Extensively modified by glycosaminoglycan groups (GAG).

Subcellular Location:

Secreted. Secreted>Extracellular space. Cell membrane>Single-pass type I membrane protein.
Note: Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with TCTEX1D4.

Restrictive clause

 

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