Product: THA11 Mouse Monoclonal Antibody
Catalog: BF9527
Description: Mouse monoclonal antibody to THA11
Application: WB
Reactivity: Human
Prediction: Mouse, Rat, Pig, Bovine, Horse, Rabbit, Dog, Xenopus
Mol.Wt.: 37 kDa; 34kD(Calculated).
Uniprot: Q96EK4

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm9527]
Specificity:
THA11 Mouse Monoclonal Antibody detects endogenous levels of total THA11.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CTG B43a; CTG B45d; HRIHFB2206; RONIN; THA11_HUMAN; THAP 11; THAP domain containing 11; THAP domain-containing protein 11; Thap11;

Immunogens

Immunogen:

A synthesized peptide derived from human THA11, corresponding to a region within the internal amino acids.

Uniprot:
Gene(ID):
Sequence:
MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTLQATVDSSQAPGSVQPAPITPTGEDVKPIDLTVQVEFAAAEGAAAAAAASELQAATAGLEAAECPMGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELREKDRLLAMAVIRKKHGM

Research Backgrounds

Function:

Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).

Subcellular Location:

Nucleus. Cytoplasm.
Note: May be regulated by shuttling of the protein between the cytoplasm and nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the THAP11 family.

Restrictive clause

 

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