AFfirm™ FKBPL Mouse Monoclonal Antibody - #BF9482
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Protocols
Product Info
Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Monoclonal [AFfirm9482]
Specificity:
FKBPL Mouse Monoclonal Antibody detects endogenous levels of total FKBPL.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL_HUMAN; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39;
Immunogens
Immunogen:
A synthesized peptide derived from human FKBPL, corresponding to a region within the internal amino acids.
Uniprot:
Gene(ID):
Expression:
Description:
FKBPL May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.
Sequence:
- Q9UIM3 FKBPL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG
Research Backgrounds
Function:
May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
Tissue Specificity:
Ubiquitously expressed with higher levels in testis.
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