AFfirm™ HOMEZ Mouse Monoclonal Antibody - #BF9436
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Protocols
Product Info
Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Monoclonal [AFfirm9436]
Specificity:
HOMEZ Mouse Monoclonal Antibody detects endogenous levels of total HOMEZ.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Homeobox and leucine zipper protein Homez; Homeodomain leucine zipper containing factor; KIAA1443;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
Q8IX15 HOMEZ_HUMAN:
Ubiquitous. Strongly expressed in adult testis and kidney as well as fetal lung and kidney.
Sequence:
- Q8IX15 HOMEZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVRGWEPPPGLDCAISEGHKSEGTMPPNKEASGLSSSPAGLICLPPISEELQLVWTQAAQTSELDSNEHLLKTFSYFPYPSLADIALLCLRYGLQMEKVKTWFMAQRLRCGISWSSEEIEETRARVVYRRDQLHFKSLLSFTHHAGRPPEEVPPPPVPAPEQVGIGIGPPTLSKPTQTKGLKVEPEEPSQMPPLPQSHQKLKESLMTPGSGAFPYQSDFWQHLQSSGLSKEQAGRGPNQSHGIGTASWNHSTTVPQPQARDKPPPIALIASSCKEESASSVTPSSSSTSSSFQVLANGATAASKPLQPLGCVPQSVSPSEQALPPHLEPAWPQGLRHNSVPGRVGPTEYLSPDMQRQRKTKRKTKEQLAILKSFFLQCQWARREDYQKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDNAVPGAPSFQDPAIPTPPPSTRSLNERAETPPLPIPPPPPDIQPLERYWAAHQQLRETDIPQLSQASRLSTQQVLDWFDSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQD
PTMs - Q8IX15 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K182 | Sumoylation | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| K412 | Ubiquitination | Uniprot | |
| T437 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| T451 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
May function as a transcriptional regulator.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous. Strongly expressed in adult testis and kidney as well as fetal lung and kidney.
Subunit Structure:
Homodimer or heterodimer (Potential). Interacts with HOXC8.
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