AFfirm™ FAKD5 Mouse Monoclonal Antibody - #BF9423
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
dJ1187M17.5; FAKD5_HUMAN; FAST kinase domain-containing protein 5; FAST kinase domains 5; FASTKD5; FLJ13149; FLJ58294;
Immunogens
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.
- Q7L8L6 FAKD5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
PTMs - Q7L8L6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| T83 | Phosphorylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| Y166 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| Y451 | Phosphorylation | Uniprot | |
| K507 | Acetylation | Uniprot | |
| T608 | Phosphorylation | Uniprot | |
| K615 | Ubiquitination | Uniprot | |
| C670 | S-Nitrosylation | Uniprot | |
| S676 | Phosphorylation | Uniprot | |
| T692 | Phosphorylation | Uniprot | |
| R704 | Methylation | Uniprot | |
| Y730 | Phosphorylation | Uniprot | |
| T761 | Phosphorylation | Uniprot | |
| S762 | Phosphorylation | Uniprot |
Research Backgrounds
Plays an important role in the processing of non-canonical mitochondrial mRNA precursors.
Mitochondrion matrix>Mitochondrion nucleoid.
Note: Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.
Found in a complex with GRSF1, DDX28, DHX30 and FASTKD2. Associates with the 12S mitochondrial rRNA (12S mt-rRNA).
Belongs to the FAST kinase family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.