AFfirm™ AE2 Mouse Monoclonal Antibody - #BF9418
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Product Info
Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Monoclonal [AFfirm9418]
Specificity:
AE2 Mouse Monoclonal Antibody detects endogenous levels of total AE2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
AE 2; AE2 anion exchanger; Anion exchange protein 2; Anion exchanger 2; B3A2_HUMAN; BAND 3-LIKE PROTEIN; BND3L; EPB3L1; erythrocyte band 3; Erythrocyte membrane protein band 3 like 1; HKB3; MPB3L; NBND3; Non-erythroid band 3-like protein; Slc4a2; Solute carrier family 4 member 2;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- P04920 B3A2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSAPRRPAKGADSFCTPEPESLGPGTPGFPEQEEDELHRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGPGRKPRRRPGASPTGETPTIEEGEEDEDEASEAEGARALTQPSPVSTPSSVQFFLQEDDSADRKAERTSPSSPAPLPHQEATPRASKGAQAGTQVEEAEAEAVAVASGTAGGDDGGASGRPLPKAQPGHRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQSGREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMPV
PTMs - P04920 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T27 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| R57 | Methylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| Y66 | Phosphorylation | Uniprot | |
| Y73 | Phosphorylation | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| T115 | Phosphorylation | Uniprot | |
| T118 | Phosphorylation | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| S144 | Phosphorylation | Uniprot | |
| T148 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| T169 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| S172 | Phosphorylation | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| T183 | Phosphorylation | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| Y233 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| T245 | Phosphorylation | Uniprot | |
| T257 | Phosphorylation | Uniprot | |
| T264 | Phosphorylation | Uniprot | |
| K274 | Methylation | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| K334 | Ubiquitination | Uniprot | |
| K362 | Ubiquitination | Uniprot | |
| K426 | Ubiquitination | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S446 | Phosphorylation | Uniprot | |
| S449 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| K505 | Ubiquitination | Uniprot | |
| K636 | Ubiquitination | Uniprot | |
| K653 | Ubiquitination | Uniprot | |
| K658 | Ubiquitination | Uniprot | |
| K893 | Ubiquitination | Uniprot | |
| K975 | Ubiquitination | Uniprot | |
| K1073 | Ubiquitination | Uniprot | |
| K1080 | Ubiquitination | Uniprot | |
| K1087 | Ubiquitination | Uniprot | |
| Y1154 | Phosphorylation | Uniprot | |
| K1156 | Ubiquitination | Uniprot | |
| Y1234 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Plasma membrane anion exchange protein of wide distribution.
Subcellular Location:
Membrane>Multi-pass membrane protein.
Family&Domains:
Belongs to the anion exchanger (TC 2.A.31) family.
Research Fields
· Organismal Systems > Digestive system > Salivary secretion.
· Organismal Systems > Digestive system > Gastric acid secretion.
· Organismal Systems > Digestive system > Pancreatic secretion.
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For Research Use Only.
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