AFfirm™ Cytochrome P450 4Z1/2 Mouse Monoclonal Antibody - #BF9400

Product: Cytochrome P450 4Z1/2 Mouse Monoclonal Antibody
Catalog: BF9400
Description: Mouse monoclonal antibody to Cytochrome P450 4Z1/2
Application: WB
Reactivity: Human
Prediction: Mouse, Rat
Mol.Wt.: 60kD; 59kD,40kD(Calculated).
Uniprot: Q86W10 | Q8N1L4

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm9400]
Specificity:
Cytochrome P450 4Z1/2 Mouse Monoclonal Antibody detects endogenous levels of total Cytochrome P450 4Z1/2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CP4Z1_HUMAN; CYP4A20; CYP4Z1; CYPIVZ1; Cytochrome P450 4Z1; Cytochrome P450 family 4 subfamily Z polypeptide 1; CP4Z2_HUMAN;CYP4Z2P;Putative inactive cytochrome P450 family member 4Z2;

Immunogens

Immunogen:
Uniprot:

Q86W10(CP4Z1_HUMAN) >>Visit HPA database.

Q8N1L4(CP4Z2_HUMAN) >>Visit HPA database.

Gene(ID):
CYP4Z1(199974)
Expression:
Q86W10 CP4Z1_HUMAN:

Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.

Q8N1L4 CP4Z2_HUMAN:

Detected at low levels in mammary gland and mammary carcinoma.

Sequence:
MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKVC

MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFEVYPELMEKYPCAVPLWVGPFTMFFNIHDPDYVKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRQDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTTTAISWIFYCLAKYPEHQQRC

PTMs - Q86W10/Q8N1L4 As Substrate

Site PTM Type Enzyme
Y55 Phosphorylation
T154 Phosphorylation
Y376 Phosphorylation
K492 Ubiquitination

Research Backgrounds

Subcellular Location:

Endoplasmic reticulum membrane>Single-pass type II membrane protein. Microsome membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.

Family&Domains:

Belongs to the cytochrome P450 family.

Subcellular Location:

Membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected at low levels in mammary gland and mammary carcinoma.

Family&Domains:

Belongs to the cytochrome P450 family.

Restrictive clause

 

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