Cytokeratin 13 Mouse Monoclonal Antibody

Product:	Cytokeratin 13 Mouse Monoclonal Antibody
Catalog:	BF8985
Description:	Mouse monoclonal antibody to Cytokeratin 13
Application:	WB
Reactivity:	Human
Prediction:	Mouse, Rat, Horse, Dog
Mol.Wt.:	50 kDa; 50kD(Calculated).
Uniprot:	P13646

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Monoclonal [AFfirm8985]

Specificity:

Cytokeratin 13 Mouse Monoclonal Antibody detects endogenous levels of total Cytokeratin 13.

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

47 kDa cytokeratin; CK-13; CK13; Cytokeratin 13; Cytokeratin-13; K13; K1C13_HUMAN; Ka13; Keratin 13; Keratin; keratin type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; MGC161462; MGC3781; type I cytoskeletal 13; Type I keratin Ka13; WSN2;

Immunogens

Immunogen:

Uniprot:

P13646(K1C13_HUMAN) >>Visit HPA database.

Gene(ID):

KRT13(3860)

Expression:

P13646 K1C13_HUMAN:

Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.

Description:

Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.

Sequence:

P13646 K1C13_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP

PTMs - P13646 As Substrate

P13646

Site	PTM Type	Source
S7	Phosphorylation	Uniprot
S8	Phosphorylation	Uniprot
S11	Phosphorylation	Uniprot
Y12	Phosphorylation	Uniprot
R27	Methylation	Uniprot
R35	Methylation	Uniprot
Y118	Phosphorylation	Uniprot
S144	Phosphorylation	Uniprot
S147	Phosphorylation	Uniprot
Y152	Phosphorylation	Uniprot
S153	Phosphorylation	Uniprot
Y155	Phosphorylation	Uniprot
Y156	Phosphorylation	Uniprot
T168	Phosphorylation	Uniprot
T170	Phosphorylation	Uniprot
Y194	Phosphorylation	Uniprot
Y238	Phosphorylation	Uniprot
Y281	Phosphorylation	Uniprot
T311	Phosphorylation	Uniprot
T316	Phosphorylation	Uniprot
T327	Phosphorylation	Uniprot
S337	Phosphorylation	Uniprot
S340	Phosphorylation	Uniprot
T404	Phosphorylation	Uniprot
Y405	Phosphorylation	Uniprot
S421	Phosphorylation	Uniprot
S422	Phosphorylation	Uniprot
S425	Phosphorylation	Uniprot
S427	Phosphorylation	Uniprot
S432	Phosphorylation	Uniprot
T434	Phosphorylation	Uniprot
T452	Phosphorylation	Uniprot
S453	Phosphorylation	Uniprot

Research Backgrounds

P13646_K1C13_HUMAN

PTMs:

O-glycosylated; glycans consist of single N-acetylglucosamine residues.

Tissue Specificity:

Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.

Subunit Structure:

Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.

Family&Domains:

Belongs to the intermediate filament family.

Research Fields

· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)

Restrictive clause

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For Research Use Only.
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AFfirm™ Cytokeratin 13 Mouse Monoclonal Antibody - #BF8985