Product: CHCHD6 Mouse Monoclonal Antibody
Catalog: BF8894
Description: Mouse monoclonal antibody to CHCHD6
Application: WB
Reactivity: Human, Mouse
Prediction: Rat, Pig, Bovine, Rabbit
Mol.Wt.: 26-29 kDa; 26kD(Calculated).
Uniprot: Q9BRQ6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Monoclonal [AFfirm8894]
Specificity:
CHCHD6 Mouse Monoclonal Antibody detects endogenous levels of total CHCHD6.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CHCH6_HUMAN; Chchd6; CHCM1; Coiled coil helix cristae morphology 1; Coiled coil helix cristae morphology protein 1; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial; Mic25; MICOS complex subunit MIC25; PPP1R23; Protein phosphatase 1 regulatory subunit 23;

Immunogens

Immunogen:

A synthesized peptide derived from human CHCHD6, corresponding to a region within the internal amino acids.

Uniprot:
Gene(ID):
Sequence:
MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG

Research Backgrounds

Function:

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Subcellular Location:

Mitochondrion inner membrane>Lipid-anchor. Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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